The NFL has officially unveiled the full schedule for the 2025-2026 season, and it’s already shaping up to be an electrifying campaign. With 272 regular-season matchups, picking the highlights was no easy task. From blockbuster rematches to grudge matches and heavyweight showdowns, the season is stacked with must-see action.
Here are 10 unmissable games you need to circle on your calendar:
Washington Commanders vs. Dallas Cowboys – Week 17 (Christmas Day)
It’s hard to beat a classic NFC East rivalry on Christmas Day. The Commanders shocked everyone last season, reaching the Conference Finals behind rookie sensation Jayden Daniels. Meanwhile, Dak Prescott and the Cowboys will be itching to bounce back after a disappointing year. Add holiday drama to this storied matchup, and you’ve got must-watch TV.
Pittsburgh Steelers vs. Green Bay Packers – Week 8
Could this be the game where Aaron Rodgers faces his former team as a Pittsburgh Steeler? While his next move remains uncertain, this potential storyline has fans buzzing. Meanwhile, Jordan Love is looking to cement his role as the Packers’ franchise QB. It’s a clash of tradition and transition, with two of the league’s most historic franchises battling it out.
Seattle Seahawks vs. Minnesota Vikings – Week 13
An Andy Dalton revenge game wasn’t on anyone’s 2025 bingo card—but here we are. Dumped by the Vikings in favour of top-10 draft pick JJ McCarthy, Dalton will be out to prove he still has plenty in the tank. Expect both QBs to put on a show in a game full of pride and playoff implications.
Detroit Lions vs. Chicago Bears – Week 2
The Bears welcome new head coach Ben Johnson—formerly the Lions’ offensive coordinator—in an emotionally charged NFC North showdown. Caleb Williams will aim to prove he belongs on the biggest stage, while Detroit tries to show their offensive firepower isn’t reliant on their departed mastermind.
Buffalo Bills vs. Cincinnati Bengals – Week 14
A clash between Josh Allen and Joe Burrow is always a headline-maker. These two quarterbacks were both in the MVP conversation last season, and their rivalry is fast becoming one of the league’s most compelling. It’s a late-season showdown that could shake up the AFC playoff picture.
Minnesota Vikings vs. Detroit Lions – Week 17 (Christmas Day)
The NFC North title could be on the line during this Christmas Day battle. With McCarthy looking to end a two-game losing streak to the Lions, and Detroit aiming to reinforce their dominance, this one has the potential to be a classic. Don’t be surprised if this game carries significant postseason implications.
Buffalo Bills vs. Baltimore Ravens – Week 1
Week 1 starts with a bang. Lamar Jackson will be on a mission after losing out on his third MVP award to Allen. It’s a game dripping with elite talent and early-season urgency. Miss it, and you’ll miss one of the best QB matchups of the year.
Buffalo Bills vs. Kansas City Chiefs – Week 9
This rivalry has become a modern classic. From playoff heartbreaks to unforgettable shootouts, Patrick Mahomes and Josh Allen always deliver. The Bills will be out for revenge, while the Chiefs aim to reassert their supremacy in the AFC.
Philadelphia Eagles vs. Detroit Lions – Week 11
Two of the NFC’s most complete teams collide in a late-season tilt that could have major Super Bowl implications. The Eagles, last year’s champions, return with something to prove, while the Lions are hungry to show they should’ve been there in the first place. A heavyweight bout, plain and simple.
Kansas City Chiefs vs. Philadelphia Eagles – Week 2 (Super Bowl Rematch)
How could this not be No. 1? The highly anticipated Super Bowl rematch features two of the NFL’s most complete rosters and iconic quarterbacks. Mahomes will be out to avenge his loss, while the Eagles will look to make a statement: last season was no fluke. It’s the ultimate tone-setter for the season ahead.
Final Thoughts
From star-studded quarterback duels to legacy-defining clashes, the 2025-2026 NFL season is loaded with storylines. These 10 games promise peak drama, intensity, and entertainment. Be sure to tune in—these matchups could shape the road to Super Bowl LX.
